Rabbit Polyclonal Antibody to HNF1A
货号：
P12458
别名：
HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P20823
规格：
目录价
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Description |
|---|
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Specification |
|
|---|---|
| Aliases | HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20 |
| Swissprot | P20823 |
| WB Predicted band size | 67 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human HNF1A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/30-1/150 |
| ELISA | 1/5000-1/10000 |
Product Image
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A172 cell, Mouse liver tissue, Hela cell lysates , Primary antibody: P12458(HNF1A Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P12458(HNF1A Antibody) at dilution 1/20. (Original magnification: ×200)
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