Rabbit Monoclonal Antibody to Thioredoxin Reductase 1
货号：
P22138
别名：
TR; TR1; TXNR; TRXR1; GRIM-12
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q16881
规格：
目录价
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Description |
|---|
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. |
Specification |
|
|---|---|
| Aliases | TR; TR1; TXNR; TRXR1; GRIM-12 |
| Entrez GeneID | 7296 |
| Swissprot | Q16881 |
| WB Predicted band size | Calculated MW: 71 kDa; Observed MW: 55 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human TXNRD1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of TXNRD1 in 3T3 lysates using Thioredoxin Reductase 1 antibody.
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Western blot analysis of TXNRD1 in K562, Hela lysates using TXNRD1 antibody.
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Immunocytochemistry analysis of TXNRD1(green) in Hela using TXNRD1 antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using TXNRD1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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