Rabbit Polyclonal Antibody to SphK2 (phospho Thr614)
货号:
P44063
别名:
SPHK2; Sphingosine kinase 2; SK 2; SPK 2
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9NRA0
规格:
目录价
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Description |
|---|
sphingosine kinase 2(SPHK2) Homo sapiens This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011], |
Specification |
|
|---|---|
| Aliases | SPHK2; Sphingosine kinase 2; SK 2; SPK 2 |
| Entrez GeneID | 56848 |
| Swissprot | Q9NRA0 |
| WB Predicted band size | 69kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SPHK2 around the phosphorylation site of Thr614. AA range:580-629 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/100 - 1/300 |
| ELISA | 1/5000 |

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