Rabbit Polyclonal Antibody to Troponin I-C (phospho Ser43)
货号:
P44015
别名:
TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P19429
规格:
目录价
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Description |
|---|
troponin I3, cardiac type(TNNI3) Homo sapiens Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008], |
Specification |
|
|---|---|
| Aliases | TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
| Entrez GeneID | 7137 |
| Swissprot | P19429 |
| WB Predicted band size | 26kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNNI3 around the phosphorylation site of Ser43. AA range:11-60 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/100 - 1/300 |
| ELISA | 1/40000 |

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