Mouse Monoclonal Antibody to TRADD
货号：
31699
别名：
Hs.89862
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15628
规格：
目录价
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Description |
|---|
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008] |
References |
|---|
| 1.Biomed Pharmacother. 2017 Sep;93:1-7. 2.Mol Neurodegener. 2017 Mar 20;12(1):26. |
Specification |
|
|---|---|
| Aliases | Hs.89862 |
| Entrez GeneID | 8717 |
| Swissprot | Q15628 |
| clone | 3A1E8 |
| WB Predicted band size | 34.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human TRADD (AA: 1-177) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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